Steroids and derivatives
Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.9% | C32H38N2O5 | 25 MG
Bazedoxifene acetate is an oral, nonsteroidal selective estrogen receptor modulator (SERM) that acts as an inhibitor of IL-6/GP130 protein-protein interactions. It is used in research for osteoporosis and pancreatic cancer.
- Small molecular GP130 inhibitor
- Inhibits STAT3 phosphorylation induced by IL-6 and IL-11
- Induces apoptosis in human pancreatic cancer cells
- Inhibits STAT3 nuclear translocation induced by IL-6
- Blocks cell migration in pancreatic cancer cells by inhibiting GP130
- Inhibits Capan-1 tumor growth in mouse models
Medchemexpress LLC Retinol, acetate, 9-cis- | 29584-22-3 | 85.0% | 328.49 | 1 MG
9-cis-Retinol acetate is a retinal derivative developed for research applications. This compound is presented as a solid, typically white to off-white in appearance, with a molecular weight of 328.49. Its purity is 85.0%, making it suitable for various scientific investigations.
- Retinal derivative.
- Intended for research use only.
- Molecular formula C22H32O2.
- Appearance is solid, white to off-white.
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years.
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month.
Cambridge Isotope Laboratories VITAMIN D3 (CHOLECALCIFEROL) UNLABELED 100 UG/ML IN ETHANOL, 1 ML
VITAMIN D3 (CHOLECALCIFEROL) UNLABELED 100 UG/ML IN ETHANOL, 1 ML
Apexbio Technology LLC Calcitriol, 1mg. Cas: 32222-06-3 MFCD: MFCD00867079. Active metabolite of vitamin D3
Calcitriol is a form of Vitamin D, is converted to metabolites more potent and rapidly acting than other forms of Vitamin D. 32222-06-3. MFCD00867079
Apexbio Technology LLC Ethinyl Estradiol 57-63-6 500mg
Ethinyl Estradiol (57-63-6) is a small-molecule estrogen receptor agonist targeting intracellular estrogen receptors It is designed to activate these receptors thereby regulating transcription of estrogen-responsive genes and influencing reproductive biology and cell proliferation pathways Ethinyl Estradiol exerts its biological activity primarily through direct binding to estrogen receptors leading to the modulation of endocrine-regulated mechanisms Based on these pharmacological properties Ethinyl Estradiol holds research potential in studies of receptor-mediated responses endocrine regulation mechanisms synthetic hormone interactions drug interactions contraceptive mechanisms and hormone-dependent physiological processes
Medchemexpress LLC Estradiol-d2-1 | 3188-46-3 | 1 MG
Estradiol-d2-1 is a deuterium-labeled Estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. It upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules
- Has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC β-Estradiol 17-acetate | 1743-60-8 | 99.9% | 1 ML
β-Estradiol 17-acetate is a metabolite of estradiol, designed for research use only in laboratory settings. It is provided for chemical synthesis and intended for use by experienced personnel in appropriately equipped facilities.
- Available in powder and pre-dissolved solution formats.
- Stable under recommended storage conditions, with specific guidance for powder and solvent forms.
- Highly soluble in DMSO for in vitro applications.
- Features established protocols for in vivo solubility using various solvent systems.
- Molecular formula C20H26O3 and molecular weight of 314.42.
- Typically appears as a white to off-white solid with a melting point of 119°C.
Sigma Aldrich Fine Chemicals Biosciences Estradiol hemihydrate European Pharmacopoeia (EP) Reference Standard | 35380-71-3 | MFCD23102821 |
Estradiol hemihydrate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 281.39 | 35380-71-3 | MFCD23102821 |
Medchemexpress LLC Estradiol 3-glucuronide | 15270-30-1 | 97.6% | 448.51 g/mol | C24H32O8 | 500 UG
Estradiol 3-glucuronide is the glucuronic acid conjugate of estradiol used as a research reagent and immunogen for studies of estrogen metabolism, antibody production, and radioimmunoassay. Supplied as a white to off-white solid for laboratory research use only.
- White to off-white solid suitable for biochemical assays.
- Used as an immunogen for antibody generation and radioimmunoassay studies.
- Applicable in research on estrogen metabolism and analytical detection methods.
- Typical purity approximately 97.6% by HPLC (batch dependent).
- Chemical formula C24H32O8; molecular weight 448.51 g/mol; CAS 15270-30-1.
- Store powder at -20°C; in solvent store at -80°C up to 6 months or -20°C for shorter term.
Sigma Aldrich Fine Chemicals Biosciences Cyproterone acetate European Pharmacopoeia (EP) Reference Standard | 427-51-0 | MFCD00864671 |
Cyproterone acetate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 416.94 | 427-51-0 | MFCD00864671 |
Medchemexpress LLC Dexamethasone (GMP) | 50-02-2 | MFCD00064136 | >99.8% | 392.46 | 50 MG
Dexamethasone (Hexadecadrol) (GMP) is a glucocorticoid receptor agonist produced using GMP guidelines. It functions as an auxiliary reagent for cell therapy manufacture.
- Increases myotubes formation and cytoplasmic lipid droplets accumulation
- Induces osteogenesis of chick periosteum cells
- Induces osteoblastic differentiation
- Stimulates differentiation of odontoblast-like cells